ALDURAZYME® is indicated for adult and pediatric patients with Hurler and Hurler-Scheie forms of Mucopolysaccharidosis type I (MPS I) and for patients with the Scheie form who have moderate to severe symptoms.1
Limitations of Use:
- The risks and benefits of treating mildly affected patients with the Scheie form have not been established.
- ALDURAZYME has not been evaluated for effects on the central nervous system manifestations of the disorder.
6-MWT = six-minute walk test; FVC = forced vital capacity; MPS I = mucopolysaccharidosis type I.
Reference: 1. ALDURAZYME [prescribing information]. Cambridge, MA: Genzyme Corporation; 2020.