TAKING ALDURAZYME
Aldurazyme will be given once weekly by intravenous (IV) infusion, meaning that the medication is delivered directly into your bloodstream. An HCP will give you this infusion, which usually take 3 to 4 hours. The initial infusion rate of 10 μg/kg/h may be increased every 15 minutes during the first hour, as tolerated, until a maximum infusion rate of 200 μg/kg/h is reached.
Here is a description of the typical process during a treatment session:
Aldurazyme treatment usually starts in the hospital
- You may meet with an HCP for a checkup on your symptoms
- As prescribed by your HCP, you will receive an Aldurazyme infusion once a week
You will be given other medications 60 mins before each Aldurazyme injection to help reduce the risk of a serious allergic reaction
- Your HCP will review and discuss the infusion process with you
- Next, your HCP will check your vital signs (pulse, blood pressure, respiration, temperature, and weight)
- The HCP will then clean a spot on your arm with alcohol and insert a small needle into the vein. A bag of liquid containing Aldurazyme is connected to the needle with IV tubing
Aldurazyme is infused over approximately 3 to 4 hours
- While receiving the infusion, you may usually lie down or sit comfortably doing activities such as reading a book or watching television
- The HCP will recheck your vital signs every 15 mins for the first hour of infusion
- When the bag is empty, a clear solution may be injected in the IV line to ensure that all the medication has been given
- Then the IV needle is removed, and vital signs are checked one more time
Your HCP will decide how long you should be monitored after your infusion is complete.
For more information about the side effects, anaphylaxis and hypersensitivity reactions, risk of acute respiratory complications, risk of acute cardiorespiratory and infusion reactions, ask your HCP.
Please see Important Safety Information below and full Prescribing Information.
Talk to your HCP about the correct dosing for you
Your HCP will want to see you regularly to check that Aldurazyme is working for you and ensure that you are taking the correct dose.
Since Aldurazyme dosing is based on weight, it is important that you attend all follow-up appointments arranged by your HCP, as changes in treatment may be required based on your weight.
Aldurazyme keeps working when you keep taking as prescribed
Regular infusions of Aldurazyme every week helps to ensure that the body has an ongoing supply of fully functional enzyme to clear GAGs.
Even if you don’t notice any symptoms, it’s important to continue to take Aldurazyme as directed, to help ensure that GAGs don’t start to build up again.
If you miss an infusion, talk to your HCP about rescheduling your next dose.